Lus piav qhia luv luv:
CAS Nr .: 7177-48-2
Molecular formula: C16H25N3O7S
Molecular Luj: 403.45
Chemical structure:
| Cov ntaub ntawv yooj yim | |
| Khoom npe | Ampicillin |
| Qib | Pharmaceutical Qib |
| Qhov tshwm sim | Dawb los yog yuav luag dawb, crystalline hmoov |
| Assay | |
| Txee lub neej | 2 Xyoo |
| Ntim | 25kg / nruas |
| Qhov xwm txheej | khaws cia rau hauv qhov chaw txias thiab qhuav |
Kev piav qhia
Raws li ib pawg penicillin ntawm cov tshuaj tua kab mob beta-lactam, Ampicillin yog thawj qhov dav-spectrum penicillin, uas muaj cov haujlwm hauv vitro tiv thaiv kab mob Gram-positive thiab Gram-negative aerobic thiab anaerobic kab mob, feem ntau siv los tiv thaiv thiab kho cov kab mob ntawm cov kab mob ua pa, tso zis. kab mob, nruab nrab pob ntseg, sinuses, plab thiab hnyuv, zais zis, thiab lub raum, thiab lwm yam. tshwm sim los ntawm cov kab mob raug. Nws kuj yog siv los kho cov kab mob gonorrhea tsis yooj yim, mob meningitis, endocarditis salmonellosis, thiab lwm yam kab mob loj los ntawm kev siv los ntawm qhov ncauj, txhaj tshuaj intramuscular lossis los ntawm kev txhaj tshuaj intravenous. Zoo li txhua yam tshuaj tua kab mob, nws tsis zoo rau kev kho mob ntawm tus kab mob.
Ampicillin ua haujlwm los ntawm kev tua cov kab mob lossis tiv thaiv lawv txoj kev loj hlob. Tom qab nkag mus rau Gram-positive thiab Gram-negative kab mob, nws ua raws li ib tug irreversible inhibitor ntawm lub enzyme transpeptidase xav tau los ntawm cov kab mob los ua rau lub cell phab ntsa, uas ua rau inhibition ntawm cell phab ntsa synthesis thiab nws thiaj li ua rau cell lysis.
Antimicrobial kev ua haujlwm
Ampicillin tsis tshua muaj zog dua li benzylpenicillin tawm tsam feem ntau cov kab mob Gram-zoo tab sis muaj zog dua tawm tsam E. faecalis. MRSA thiab kab mob Str. pneumoniae nrog txo qis rau benzylpenicillin tiv taus. Feem ntau pawg D streptococci, anaerobic Gram-positive cocci thiab bacilli, suav nrog L. monocytogenes, Actinomyces spp. thiab Arachnia spp., yog raug. Mycobacteria thiab nocardia tiv taus.
Ampicillin muaj cov haujlwm zoo sib xws rau benzylpenicillin tiv thaiv N. gonorrhoeae, N. meningitidis thiab Mor. kab mob catarrhalis. Nws yog 2-8 npaug ntau dua li benzylpenicillin tiv thaiv H. influenzae thiab ntau Enterobacteriaceae, tab sis β-lactamase-producing hom yog resistant. Pseudomonas spp. yog cov resistant, tab sis Bordetella, Brucella, Legionella thiab Campylobacter spp. feem ntau raug. Qee cov Gram-negative anaerobes xws li Prevotella melaninogenica thiab Fusobacterium spp. Cov kab mob kis tau yooj yim, tab sis B. fragilis tiv taus, xws li mycoplasmas thiab rickettsiae.
Kev ua haujlwm tawm tsam molecular class A β-lactamase-producing strains of staphylococci, gonococci, H. influenzae, Mor. catarrhalis, qee yam Enterobacteriaceae thiab B. fragilis yog txhim kho los ntawm kev muaj β-lactamase inhibitors, tshwj xeeb clavulanic acid.
Nws cov kab mob bactericidal zoo ib yam li benzylpenicillin. Bactericidal synergy tshwm sim nrog aminoglycosides tawm tsam E. faecalis thiab ntau enterobacteria, thiab nrog mecillinam tiv thaiv ib tug xov tooj ntawm ampicillin-resistant enterobacteria.
