Cov ntaub ntawv yooj yim | |
Lwm lub npe | Acetylsalicylic acid |
Khoom npe | Aspirin |
Qib | Pharma Qib / Pub Qib |
Qhov tshwm sim | Dawb crystalline hmoov |
Assay | 99% |
Txee lub neej | 2 xyoo |
Yam ntxwv | Me ntsis soluble hauv dej, soluble hauv ethanol, ethyl ether, chloroform, sodium hydroxide tov thiab sodium carbonate tov. |
Cia | Khaws rau hauv qhov chaw txias qhuav |
Khoom piav qhia
Aspirin, tseem hu ua acetylsalicylic acid (ASA), yog ib yam tshuaj siv los txo qhov mob, ua npaws, lossis o. Cov mob tshwj xeeb uas cov tshuaj aspirin siv los kho muaj xws li kab mob Kawasaki, pericarditis, thiab kub taub hau. Aspirin yog cov tshuaj siv dav tshaj plaws hauv ntiaj teb.
Muaj nuj nqi
Acetylsalicylic acid muaj antipyretic analgesic, anti-inflammatory thiab anti-rheumatism nyhuv, yog vim li cas nws yog feem ntau siv rau kub taub hau, mob taub hau, mob nqaij, neuralgia, rheumatic fever, mob rheumatic mob caj dab, gout, thiab lwm yam. Nws kuj tseem muaj cov nyhuv antiplatelet aggregation, thiab tuaj yeem siv los tiv thaiv cov hlab ntsha thrombosis, atherosclerosis, ntuav cerebral ischemia thiab myocardial infarction; Tsis tas li ntawd, acetylsalicylic acid kuj tuaj yeem siv los kho cov kab mob biliary kab mob roundworm kab mob thiab kis kab mob ko taw.
Pharmacological kev ua
Acetylsalicylic acid yog ib qho tshuaj tua kab mob antipyretic, nrog rau lub luag haujlwm ntawm platelet aggregation. Acetylsalicylic acid nyob rau hauv lub cev muaj cov yam ntxwv ntawm antithrombotic, tuaj yeem txo qhov tsim ntawm cov hlab ntshav txhaws nyob ib puag ncig cov hlab ntsha, thiab inhibit qhov tso tawm ntawm platelet teb thiab endogenous ADP, 5-HT, thiab lwm yam, yog li inhibit theem thib ob uas tsis yog thawj zaug. theem ntawm platelet aggregation. Cov txheej txheem ntawm kev txiav txim ntawm acetylsalicylic acid yog ua kom platelets cyclooxygenase acetylation, yog li inhibiting tsim ntawm lub nplhaib peroxide, thiab TXA2 tsim kuj txo thiab. Nyob rau lub sijhawm no, ua rau platelet membrane protein acetylation, thiab inhibit platelet membrane enzyme, uas pab inhibit platelet muaj nuj nqi. Raws li cov cyclooxygenase inhibited, nws cuam tshuam cov hlab ntsha phab ntsa synthesized los ua PGI2, platelet TXA2 hluavtaws enzymes kuj yuav inhibited; yog li nws yuav cuam tshuam kev tsim ntawm TXA2 thiab PGI2 thaum nws koob tshuaj loj. Haum rau cov kab mob plawv ischemic, tom qab percutaneous transluminal coronary angioplasty lossis coronary artery bypass grafting, tiv thaiv tsis pub dhau ischemic stroke, myocardial infarction thiab txo qhov tshwm sim ntawm arrhythmia. Acetylsalicylic acid kuj tuaj yeem siv rau hauv kev kho mob ntawm biliary tract roundworm kab mob thiab kis las ko taw.
Daim ntawv thov
Nws yog thawj zaug thov, nrov tshaj plaws thiab feem ntau siv tshuaj antipyretic analgesics anti-rheumatism tshuaj, muaj cov yam ntxwv ntawm pharmacological teebmeem raws li antipyretic-analgesic thiab anti-inflammatory, anti-platelet aggregation thiab ua hauj lwm sai thiab zoo. Kev noj ntau dhau tuaj yeem kuaj pom tau yooj yim thiab kho, nrog rau qhov tsis tshua muaj tshwm sim. Feem ntau siv los ua npaws txias, mob taub hau, neuralgia, mob pob qij txha, mob nqaij, mob rheumatic fever, mob khaub thuas sib deev mob caj dab, mob caj dab rheumatoid thiab toothache, thiab lwm yam. Muaj npe nyob rau hauv National Essential Medicine List. Acetylsalicylic acid kuj ua haujlwm raws li qhov nruab nrab ntawm lwm cov tshuaj.