Lus piav qhia luv luv:
CAS Nr .: 27164-46-1
Cov mis mos molecular: C14H15N8NaO4S3
Molecular Luj: 478.5
Chemical structure:
| Cov ntaub ntawv yooj yim | |
| Khoom npe | Cefazolin sodium ntsev |
| CAS Nr. | 27164-46-1 : kuv |
| Qhov tshwm sim | Dawb rau Off-White crystalline hmoov |
| Qib | Pharma Qib |
| Cia | Khaws nyob rau hauv qhov chaw tsaus, inert cua, 2-8 ° C |
| Txee lub neej | 2 xyoo |
| Kev ruaj ntseg | Ruaj khov, tab sis tej zaum yuav kub hnyiab tau - khaws cia hauv qhov txias txias. Tej zaum yuav discolor thaum raug lub teeb - khaws cia hauv qhov tsaus ntuj. Incompatible nrog muaj zog oxidizing neeg sawv cev. |
| Pob | 25kg / Nruas |
Product Description
Ib qho tshuaj tua kab mob semi hluavtaws uas muaj cephalosporins hauv cov molecule ntawm cephalosporins. Txhais li Xianfeng mycin. nyob rau β-Lactam tshuaj tua kab mob, yog β- Cov derivatives ntawm 7-aminocephalosporanic acid (7-ACA) nyob rau hauv lactam tshuaj tua kab mob muaj xws li bactericidal mechanisms. Hom tshuaj no tuaj yeem rhuav tshem cov phab ntsa ntawm tes ntawm cov kab mob thiab tua lawv thaum lub sijhawm ua me nyuam. Nws muaj kev xaiv zoo rau cov kab mob thiab yuav luag tsis muaj tshuaj lom rau tib neeg, nrog rau qhov zoo xws li cov kab mob dav dav, cov kab mob muaj zog tiv thaiv kab mob, tiv thaiv penicillin enzymes, thiab kev tsis haum tshuaj tsawg dua piv rau penicillin. Yog li nws yog ib qho tshuaj tua kab mob tseem ceeb nrog kev ua haujlwm siab, tsis muaj tshuaj lom, thiab siv dav hauv kev kho mob. Thawj tiam cephalosporins tau tsim ua ntej, nrog cov tshuaj tua kab mob muaj zog dua piv rau Chemicalbook, nqaim cov kab mob tua kab mob, thiab cov tshuaj tiv thaiv kab mob zoo Gram zoo dua li cov kab mob Gram tsis zoo. Ua los ntawm Staphylococcus aureus β- Lactamase ruaj khov thiab tuaj yeem cuam tshuam cov kab mob tsis zoo β- Lactamases tsis ruaj khov thiab tseem tuaj yeem tsim los ntawm ntau cov kab mob Gram tsis zoo β- puas los ntawm lactamases. Cefazolin sodium yog ib tug semi hluavtaws thawj tiam cephalosporin uas muaj cov tshuaj tua kab mob tiv thaiv kab mob gram-positive thiab gram-negative. Nws yog feem ntau siv rau hauv cov kab mob ntawm cov kab mob ua pa, urogenital system, daim tawv nqaij mos, pob txha thiab pob qij txha, thiab cov kab mob biliary tshwm sim los ntawm cov kab mob rhiab heev, nrog rau cov kab mob endocarditis, sepsis, pharyngeal thiab pob ntseg. Nws muaj zog tiv thaiv kab mob gram-zoo xws li Staphylococcus aureus thiab Streptococcus (tsis suav Enterococcus), thiab yog superior rau thib peb tiam cephalosporins.
Siv tshuaj
Cefazolin (Ancef, Kefzol) yog ib qho ntawm cov semisyntheticcephalosporins uas C-3 acetoxy muaj nuj nqi tau hloov pauv los ntawm thiol-muaj heterocycle-ntawm no, 5-methyl-2-thio-1,3,4-thiadiazole. Nws kuj muaj cov tetrazolylacetyl acylating pawg me me. Cefazolin tau tso tawm hauv xyoo 1973 ua dej-soluble sodium ntsev. Nws yog active nkaus xwb los ntawm parenteral tswj.
Cefazolin muab cov ntshav qab zib ntau dua, qeeb renalclearance, thiab ib nrab lub neej ntev dua li lwm cov thawj tiam cephalosporins. Nws yog kwv yees li 75% cov protein khi hauv cov ntshav, tus nqi siab dua rau feem ntau lwm cov cephalosporins. Thaum ntxov hauv vitro thiab cov kev tshawb fawb soj ntsuam pom tau tias cefazolin muaj zog dua tiv thaiv Gram-negative bacilli tab sis tsawg dua active against Gram-positive cocci dua li cephalothin orcephaloridine. Qhov tshwm sim ntawm thrombophlebitis tom qab txhaj tshuaj thiab mob ntawm qhov chaw ntawm intramuscularinjection tshwm sim yog qhov qis tshaj ntawm parenteralcephalosporins.
