Lus piav qhia luv luv:
CAS nr:24729-96-2
Cov mis mos molecular: C18H34ClN2O8PS
Molecular Luj: 504.96
Chemical structure:
| Cov ntaub ntawv yooj yim | |
| Khoom npe | Clindamycin Phosphate |
| Qib | Pharma qib |
| Qhov tshwm sim | hmoov dawb |
| Assay | 95% |
| Txee lub neej | 2 xyoo |
| Ntim | 25kg / nruas |
| Qhov xwm txheej | Stable, tab sis cia txias. Incompatible nrog muaj zog oxidizing neeg sawv cev, calcium gluconate, barbiturates, magnesium sulfate, phenytoin, B pab pawg neeg sodium vitamins. |
Kev piav qhia
Clindamycin phosphate yog cov dej-soluble ester ntawm cov tshuaj tua kab mob semisynthetic uas tsim los ntawm 7 (S)-chloro-hloov ntawm 7 (R)-hydroxyl pawg ntawm niam txiv tshuaj tua kab mob, lincomycin. Nws yog ib qho derivative ntawm lincomycin (ib lincosamide). Nws muaj feem ntau cov kab mob bacteriostatic tawm tsam Gram-zoo aerobes thiab ntau yam anaerobicbacteria. Nws yog ib hom tshuaj tua kab mob uas siv los kho cov kab mob. Cov no tuaj yeem suav nrog kev kis kab mob ua pa, septicaemia, peritonitis thiab kab mob pob txha. Nws kuj yog siv los kho pob txuv nruab nrab mus rau hnyav.
Siv
Clindamycin phosphate yog siv tshuaj pleev ib ce los yog ua ke nrog benzoyl peroxide hauv kev kho mob pob txuv vulgaris. Hauv kev ntsuas cov txiaj ntsig zoo ntawm cov tshuaj pleev clindamycin, qhov ua tau ntawm cov teebmeem GI loj cuam tshuam nrog cov tshuaj yuav tsum raug txiav txim siab. Kev kho mob ntawm pob txuv vulgaris yuav tsum yog tus kheej thiab nquag hloov kho nyob ntawm hom pob txuv qhov txhab uas ua rau muaj zog thiab cov lus teb rau kev kho. Cov tshuaj tiv thaiv kab mob, suav nrog clindamycin, feem ntau yog siv los kho pob txuv me me mus rau nruab nrab. Txawm li cas los xij, kev siv tshuaj tua kab mob raws li kev kho mob monotherapy tuaj yeem ua rau cov kab mob tsis zoo; Cov tshuaj tiv thaiv no cuam tshuam nrog kev txo qis kev kho mob.Tshuaj clindamycin yog qhov tshwj xeeb tshaj yog thaum siv nrog benzoyl peroxide lossis tshuaj pleev retinoids. Cov txiaj ntsig ntawm kev tshawb fawb soj ntsuam qhia tau hais tias kev sib xyaw ua ke ua rau txo qis ntawm tag nrho cov kab mob ntawm 50-70%.
Clindamycin 2-phosphate yog aa ntsev ntawm clincamycin, semi-synthetic lincosamide. Cov ntsev yog npaj los ntawm kev xaiv phosphorylation ntawm 2-hydroxy moiety ntawm qab zib ntawm clindamycin. Kev taw qhia txog cov phosphate tuaj yeem txhim kho solubility rau cov tshuaj txhaj tshuaj. Zoo li lwm cov tswv cuab ntawm tsev neeg lincosamide, clindamycin 2-phosphate yog cov tshuaj tua kab mob dav dav nrog kev ua haujlwm tiv thaiv kab mob anaerobic thiab protozoans. Clindamycin ua los ntawm kev khi rau 23S ribosomal subunit, thaiv cov protein synthesis.
