Cov ntaub ntawv yooj yim | |
Khoom npe | Folate ntsiav tshuaj |
Lwm lub npe | Folic Acid Tablet, Activated Folate Tablet, Active Folic Acid Tablet, thiab lwm yam. |
Qib | Qib zaub mov |
Qhov tshwm sim | Raws li cov neeg siv khoom xav tau Hloov, Oval, Oblong, Daim duab peb sab, Pob zeb diamond thiab qee cov duab tshwj xeeb yog txhua yam muaj. |
Txee lub neej | 2-3 xyoos, raws li lub khw muag khoom |
Ntim | Bulk, fwj, blister packs lossis cov neeg siv khoom xav tau |
Qhov xwm txheej | Khaws rau hauv cov thawv nruj, tiv thaiv los ntawm lub teeb. |
Kev piav qhia
Qhov cuam tshuam ntawm folic acid ntawm cov kab mob feem ntau yog tshwm sim hauv cov hauv qab no: koom nrog cov metabolism hauv cov khoom siv caj ces thiab cov protein; cuam tshuam rau tsiaj kev loj hlob; cuam tshuam rau lub secretion ntawm tsiaj pancreas; txhawb kev loj hlob ntawm cov tsiaj; thiab txhim kho lub cev tiv thaiv kab mob.
Methyltetrahydrofolate ib txwm hais txog 5-methyltetrahydrofolate, uas muaj kev ua haujlwm ntawm kev noj qab haus huv lub cev thiab ntxiv cov folic acid. 5-Methyltetrahydrofolate yog ib yam khoom uas muaj lub luag haujlwm tseem ceeb uas hloov los ntawm folic acid los ntawm cov tshuaj biochemical hauv tib neeg lub cev. Nws tuaj yeem siv ncaj qha los ntawm lub cev hauv ntau txoj hauv kev metabolic los tswj lub cev ua haujlwm ib txwm muaj, yog li ua lub luag haujlwm hauv kev txhawb nqa lub cev.
Muaj nuj nqi
Folic acid yog ib hom B vitamins, tseem hu ua pteroylglutamic acid. 5-methyltetrahydrofolate yog cov kauj ruam kawg hauv cov metabolism thiab kev hloov pauv ntawm folic acid hauv lub cev. Vim nws txoj haujlwm ua haujlwm, nws tseem hu ua active. Folic acid yog ib feem ntawm cov tshuaj folic acid hauv lub cev.
Vim hais tias cov qauv molecular ntawm 5-methyltetrahydrofolate tuaj yeem nqus ncaj qha los ntawm lub cev yam tsis muaj kev cuam tshuam cov txheej txheem metabolic, nws muaj dav hauv lub cev hlwb. Piv nrog folic acid, nws yooj yim dua los ntxiv cov khoom noj rau lub cev, tshwj xeeb tshaj yog rau cov poj niam uas xav tau kev npaj rau cev xeeb tub thiab cov poj niam cev xeeb tub thaum cev xeeb tub.
Folic acid yog ib qho ntawm cov vitamins tseem ceeb rau kev loj hlob thiab kev loj hlob ntawm lub cev hlwb. Nws qhov tsis txaus yuav cuam tshuam rau kev ua haujlwm ntawm lub cev ntawm tib neeg lub cev. Ntau cov ntaub ntawv tau tshaj tawm tias qhov tsis txaus ntawm folic acid yog cuam tshuam ncaj qha rau neural tube defects, megaloblastic anemia, cleft di ncauj thiab palate, kev nyuaj siab, qog thiab lwm yam kab mob.
Neural tube malformations (NTDs)
Neural tube malformations (NTDs) yog ib pab pawg ntawm cov teeb meem tshwm sim los ntawm kev kaw tsis tiav ntawm lub raj neural thaum lub sij hawm embryonic txoj kev loj hlob, xws li anencephaly, encephalocele, spina bifida, thiab lwm yam, thiab yog ib qho ntawm feem ntau cov kab mob neonatal defects. Xyoo 1991, British Medical Research Council tau lees paub thawj zaug tias cov tshuaj folic acid ntxiv ua ntej thiab tom qab cev xeeb tub tuaj yeem tiv thaiv qhov tshwm sim ntawm NTDs thiab txo qhov tshwm sim ntawm 50-70%. Kev tiv thaiv cov nyhuv ntawm folic acid ntawm NTDs tau raug suav hais tias yog ib qho kev tshawb pom kev kho mob zoo tshaj plaws ntawm lub xyoo pua 20th.
Megaloblastic anemia (MA)
Megaloblastic anemia (MA) yog ib hom mob ntshav qab zib uas tshwm sim los ntawm kev puas tsuaj hauv DNA synthesis los ntawm qhov tsis muaj folic acid lossis vitamin B12. Nws muaj ntau dua hauv cov menyuam mos thiab cov poj niam cev xeeb tub. Kev loj hlob ntawm tus me nyuam hauv plab yuav tsum muaj ntau ntawm folic acid reserves hauv niam lub cev. Yog hais tias folic acid reserves yog depleted thaum lub sij hawm cev xeeb tub los yog thaum ntxov postpartum, megaloblastic anemia yuav tshwm sim nyob rau hauv lub fetus thiab leej niam. Tom qab ntxiv cov tshuaj folic acid, tus kab mob tuaj yeem kho tau sai thiab kho.
Folic acid thiab cleft di ncauj thiab palate
Cleft di ncauj thiab palate (CLP) yog ib qho ntawm feem ntau congenital yug tsis xws luag. Qhov ua rau ntawm daim di ncauj thiab palate tseem tsis tau meej. Folic acid supplementation thaum cev xeeb tub thaum ntxov tau raug pov thawj los tiv thaiv kev yug menyuam ntawm daim di ncauj thiab palate.
Lwm yam mob
Folic acid deficiency tuaj yeem ua rau muaj kev phom sij loj rau cov niam thiab cov menyuam, xws li kev nchuav menyuam, yug ntxov ntxov, yug me nyuam tsis txaus, plab plab thiab kev loj hlob qeeb. Ntau cov ntaub ntawv tshaj tawm hais tias Alzheimer's kab mob, kev nyuaj siab, thiab kev tsis zoo ntawm lub paj hlwb hauv cov menyuam yug tshiab thiab lwm yam kab mob hauv lub hlwb yog txhua yam cuam tshuam nrog folic acid deficiency. Tsis tas li ntawd, tsis muaj folic acid kuj tuaj yeem ua rau cov qog nqaij hlav (mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, mob qog noj ntshav, thiab lwm yam), mob atrophic gastritis, colitis, kab mob plawv thiab kab mob cerebrovascular, nrog rau lwm yam kab mob xws li glossitis thiab lwm yam. kev loj hlob tsis zoo. Cov neeg laus uas tsis muaj folic acid thiab haus cawv ntau dhau tuaj yeem hloov cov qauv ntawm lawv cov hnyuv mucosa.
Daim ntawv thov
1. Cov poj niam thaum cev xeeb tub thiab thaum ntxov cev xeeb tub.
2. Cov neeg mob ntshav qab zib.
3. Cov neeg uas muaj homocysteine ntau.