Lus piav qhia luv luv:
CAS Nr .: 59-05-2
Molecular formula: C20H22N8O5
Molecular Luj: 454.45
Chemical structure:
| Cov ntaub ntawv yooj yim | |
| Khoom npe | Methotrexate |
| Qib | qib tshuaj |
| Qhov tshwm sim | txiv kab ntxwv-daj crystalline hmoov. |
| Assay | 99% |
| Txee lub neej | 2 Xyoo |
| Ntim | 25kg / thawv |
| Yam ntxwv | Stable, tab sis lub teeb rhiab heev thiab hygroscopic. Incompatible nrog muaj zog acids, muaj zog oxidizing neeg sawv cev. |
| Qhov xwm txheej | Khaws nyob rau hauv qhov chaw tsaus, Inert cua, Khaws rau hauv lub freezer, hauv qab -20 ° C |
Methotrexate yog dab tsi?
Methotrexate rhiab heev rau hydrolysis, oxidation thiab lub teeb. Insoluble hauv dej. Methotrexate decomposes nyob rau hauv heev acidic los yog alkaline tej yam kev mob. Methotrexate tsis sib haum nrog cov tshuaj muaj zog oxidizing thiab muaj zog acids.
Methotrexate yog ib qho tshuaj siv rau kev kho mob qog noj ntshav, tseem hu ua cytotoxic tshuaj. Txhawm rau txo nws cov cytotoxicity, nws tuaj yeem siv ua ke nrog calcium leucovorin. Nws yog feem ntau siv rau kev kho mob ntawm tus mob leukemia (mob lymphocytic leukemia), mob cancer mis, malignant mole thiab choriocarcinoma, mob taub hau thiab caj dab, mob qog noj ntshav, mob qog noj ntshav, txha caj qaum meningeal infiltration, mob ntsws cancer, mob qog noj ntshav, mob qog noj ntshav, refractory. psoriasis vulgaris, dermatomyositis, lub cev myositis, ankylosing spondylitis o, Crohn's kab mob, psoriasis thiab psoriatic mob caj dab, Behcet's kab mob thiab kab mob autoimmune. Methotrexate yog ib qho tshuaj tiv thaiv kab mob thiab tuaj yeem siv los kho cov txheej txheem ntawm rheumatism nrog kev ua tau zoo tshwj xeeb hauv kev kho mob synovial ntawm rheumatoid mob caj dab thiab yog cov tshuaj nquag siv los kho cov kab mob rheumatoid.
Daim ntawv thov kho mob
Nws muaj txiaj ntsig zoo hauv kev kho mob leukemia nrog kev ua tau zoo dua hauv cov neeg mob menyuam yaus. Nws muaj txiaj ntsig zoo hauv kev kho mob choriocarcinoma thiab malignant mole. Kev tswj hwm koob tshuaj ntau tau zoo hauv kev kho mob osteosarcoma, cov nqaij mos mos sarcoma, mob ntsws cancer, qog nqaij hlav qog noj ntshav, mob qog noj ntshav mis, thiab qog noj ntshav ntawm zes qe menyuam. Nws tseem muaj txiaj ntsig zoo hauv kev kho mob qog noj ntshav taub hau thiab caj dab, mob qog noj ntshav siab thiab mob qog noj ntshav. Arterial infusion ntawm cov khoom no muaj cov txiaj ntsig zoo hauv kev kho mob qog noj ntshav hauv lub taub hau thiab caj dab thiab mob qog noj ntshav. Txawm li cas los xij, nws tsis tshua siv los kho psoriasis thiab psoriasis.
